Sometimes I use USB to install non-windows stuff and then I may write image directly to USB with Etcher tool etc. These images may contain multiple partitions and returning USB back to single volume fat drive can be tricky. Windows has inbuilt tool called diskpart which usually can be used to clean USB disk and recover it back to single partition mode.
Open Command Prompt/Powershell as admin, run command diskpart (do not insert USB yet), then in diskpart: